Drench, permeating pants (10)
I believe the answer is:
impregnate
'drench' is the definition.
(I know that drench is a more specific form of impregnate)
'permeating pants' is the wordplay.
'pants' is an anagram indicator (UK informal term for 'nonsense' or 'rubbish').
'permeating' with letters rearranged gives 'IMPREGNATE'.
(Other definitions for impregnate that I've seen before include "soak" , "Saturate - permeating (anag)" , "Infuse" , "Saturate with a substance" , "Fill" .)