Drink in the end creates flipping trouble (4)
I believe the answer is:
soda
'drink' is the definition.
(soda is a kind of drink)
'end creates flipping trouble' is the wordplay.
'end' says to take the final letters.
'flipping' shows that the letters should be reversed in order.
'trouble' becomes 'ado' (both can mean bother or commotion).
The last letter of 'creates' is 's'.
'ado' backwards is 'oda'.
's'+'oda'='SODA'
'in the' acts as a link.
(Other definitions for soda that I've seen before include "pressurised liquid" , "fizz" , "Fizzy water, goes well with whiskey" , "In the US, a sweet fizzy drink" , "Type of bread, water or fountain" .)