Drone hurt unfortunate male (5)
I believe the answer is:
thrum
'drone' is the definition.
(I've seen this before)
'hurt unfortunate male' is the wordplay.
'unfortunate' is an anagram indicator.
'male' becomes 'm' (common abbreviation).
'hurt' with letters rearranged gives 'thru'.
'thru'+'m'='THRUM'
(Other definitions for thrum that I've seen before include "go on and on" , "Make monotonous sound as on guitar" , "Perform monotonously" , "Strum; thread end" , "Continuous rhythmic humming sound" .)