Drool with yen for bondage (7)
I believe the answer is:
slavery
'bondage' is the definition.
('slavery' can be a synonym of 'bondage')
'drool with yen' is the wordplay.
'drool' becomes 'slaver' ('slaver' can be a synonym of 'drool').
'with' means one lot of letters go next to another.
'yen' becomes 'y'.
'slaver'+'y'='SLAVERY'
'for' acts as a link.
(Other definitions for slavery that I've seen before include "Bondage" , "State of subjugation" , "Extreme drudgery" .)