Drop everything after a fresh start (4)
I believe the answer is:
fall
'drop' is the definition.
(I know that drop can be written as fall)
'everything after a fresh start' is the wordplay.
'everything' becomes 'all' (all things).
'after' says to put letters next to each other.
'start' indicates taking the first letters.
The initial letter of 'fresh' is 'f'.
'all' after 'f' is 'FALL'.
(Other definitions for fall that I've seen before include "Trip over - flag" , "Keel over" , "The American autumn" , "three months in America" , "What Americans call autumn" .)