Crossword Genius

Drop litter and lose it (4,7)

Ross

I believe the answer is:

have kittens

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'lose it' is the definition.
(I've seen this in another clue)

I don't understand the remainder of the clue.

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(Other definitions for have kittens that I've seen before include "Be extremely nervous (as a queen might)" , "Shake with nerves" , "Blow up" , "produce cute delivery" .)

I've seen this clue in The Independent.
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