Drug gets rodents off their face (3)
I believe the answer is:
ice
'drug' is the definition.
(I know that ice is a type of controlled substance)
I don't understand the remainder of the clue.
Can you help me to learn more?
(Other definitions for ice that I've seen before include "Cool down" , "Decorate with frosting" , "Do cake decoration" , "dessert" , "Some number" .)