Drug smuggler's refusal to carry Arabian cocaine at first (5)
I believe the answer is:
narco
'drug smuggler's' is the definition.
I know nothing about this answer so I cannot judge whether this works.
'refusal to carry arabian cocaine at first' is the wordplay.
'refusal' becomes 'no' (saying no to something).
'to carry' indicates putting letters inside.
'arabian' becomes 'Ar.' (abbreviation in Chambers).
'at first' suggests taking the first letters.
The first letter of 'cocaine' is 'c'.
'ar'+'c'='arc'
'no' enclosing 'arc' is 'NARCO'.
Can you help me to learn more?
(Other definitions for narco that I've seen before include "Drugs agent (US slang)" , "Member of US drugs squad" , "American drug agent" , "Drug trafficker" .)