Drugs grasped by both hands eliciting a sideways look (4)
I believe the answer is:
leer
'a sideways look' is the definition.
(to leer is to look at unpleasantly)
'drugs grasped by both hands' is the wordplay.
'drugs' becomes 'ee' (I've seen this in other clues).
'grasped by' means one lot of letters goes inside another (I've seen this in other clues).
'both hands' becomes 'lr' (abbreviations for left and right).
'ee' placed within 'lr' is 'LEER'.
'eliciting' is the link.
(Other definitions for leer that I've seen before include "Gaze lasciviously at" , "Look suggestively" , "Look lasciviously at" , "Lewd look" , "Give lascivious look" .)