Drunk, beginning to totter and puke? (6,2)
I believe the answer is:
tanked up
'drunk' is the definition.
'beginning to totter and puke?' is the wordplay.
'beginning' suggests taking the first letters.
'totter' indicates anagramming the letters.
The initial letter of 'to' is 't'.
'and'+'puke'='andpuke'
'andpuke' with letters rearranged gives 'ankedup'.
't'+'ankedup'='TANKED-UP'
I've seen this clue in The Independent.
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