Drunk man is supple (5)
I believe the answer is:
lithe
'supple' is the definition.
(synonyms)
'drunk man' is the wordplay.
'drunk' becomes 'lit' (slang term).
'man' becomes 'he' (pronoun for a man).
'lit'+'he'='LITHE'
'is' acts as a link.
(Other definitions for lithe that I've seen before include "able to move supply" , "Elastic" , "Don -, opera by Verdi" , "Svelte" , "flex with no difficulty" .)