Drunk Meg's pint - a crafty mixture of the Black Stuff and water, for instance (8)
I believe the answer is:
pigments
'a crafty mixture of the black stuff and water for instance' is the definition.
I can't tell whether this defines the answer.
'drunk meg's pint' is the wordplay.
'drunk' indicates anagramming the letters.
'megs'+'pint'='megspint'
'megspint' with letters rearranged gives 'PIGMENTS'.
Can you help me to learn more?
(Other definitions for pigments that I've seen before include "Colouring substances" , "Colours" , "They give colour to oil, water etc." .)