Drunk trembled, wine causing confusion (12)
I believe the answer is:
bewilderment
'confusion' is the definition.
(bewilderment is a kind of confusion)
'drunk trembled wine' is the wordplay.
'drunk' indicates anagramming the letters.
'trembled'+'wine'='trembledwine'
'trembledwine' anagrammed gives 'BEWILDERMENT'.
'causing' acts as a link.
(Other definitions for bewilderment that I've seen before include "utter confusion!" , "Not knowing what to do" , "Perplexity, confusion" .)