Drunk wanting to destroy (4)
I believe the answer is:
blot
'destroy' is the definition.
(thesaurus)
'drunk wanting to' is the wordplay.
'drunk' becomes 'blotto' (slang term).
'wanting' is a deletion indicator (wanting can mean lacking).
'blotto' with 'to' removed is 'BLOT'.
(Other definitions for blot that I've seen before include "Ink mark" , "Don't do it to your copybook" , "Dark mark/stain" , "bad mark" , "Dry piece of writing" .)