Drunk worked hard — time to quit? (5)
I believe the answer is:
oiled
'drunk' is the definition.
(I've seen this before)
'worked hard time to quit?' is the wordplay.
'worked hard' becomes 'toiled' (I've seen this before).
'time' becomes 't'.
'to quit?' is a deletion indicator.
'toiled' with 't' taken away is 'OILED'.
(Other definitions for oiled that I've seen before include "tipsy" , "Besotted" , "Oldie (anag)" , "Anointed" , "Lubricated (with drink?)" .)