Duck is about to depart from the east (5)
I believe the answer is:
eider
'duck' is the definition.
(eider is a type of duck)
I don't understand how the rest of the clue works.
Can you help me to learn more?
(Other definitions for eider that I've seen before include "Reed I make into a duck" , "Sea duck with soft down" , "Source of fine soft down" , "Duck known for down" , "Large sea duck" .)