During two days US player once ran (6)
I believe the answer is:
dashed
'ran' is the definition.
(dashing is a kind of running)
'during two days us player once' is the wordplay.
'during' indicates putting letters inside.
'two' says to double the letters.
'days' becomes 'd' (abbreviation for days).
'us player once' becomes 'Ashe' (tennis player Arthur Ashe).
'd' duplicated is 'dd'.
'dd' enclosing 'ashe' is 'DASHED'.
(Other definitions for dashed that I've seen before include "Confounded" , "completely destroyed" , "Sprinted or cast down" , "Jolly" , "Sprinted, rushed" .)