Dutch city was the first to get up a newspaper (5)
I believe the answer is:
delft
'dutch city' is the definition.
'was the first to get up a newspaper' is the wordplay.
'was the first' becomes 'led' (to lead is to go first).
'to get up' says the letters should be written backwards.
'a newspaper' becomes 'FT' (Financial Times newspaper).
'led' in reverse letter order is 'del'.
'del'+'ft'='DELFT'
(Other definitions for delft that I've seen before include "Dutch pottery style" , "South Holland pottery town" , "Netherlands town famed for pottery" , "Blue and white earthenware (from Holland)" , "Dutch glazed ware" .)