E in solo transposed up a third throughout (5)

I believe the answer is:
along
'throughout' is the definition.
(I've seen this before)
I don't understand how the rest of the clue works.
Can you help me to learn more?
(Other definitions for along that I've seen before include "Forward - in a line" , "Beside - as groups often sing!" , "Moving in a constant direction on (something)" , "For the length of" , "With a forward motion: in accompaniment" .)
