Eat and throw up, creating trouble (3,5)
I believe the answer is:
hot water
'trouble' is the definition.
(to get in hot water is to get in trouble)
'eat and throw up' is the wordplay.
'and' means one lot of letters go next to another.
'up' is an anagram indicator (letters get chucked up).
'eat'+'throw'='eatthrow'
'eatthrow' is an anagram of 'HOT WATER'.
'creating' acts as a link.
(Other definitions for hot water that I've seen before include "The naughty get in it" , "Uncomfortable predicament to be in?" , "that comes at bath time?" , "This could mean trouble!" , "Kind of trouble, could be scalding" .)