Edition of paper missing leader (5)
I believe the answer is:
issue
'edition' is the definition.
(thesaurus)
'paper missing leader' is the wordplay.
'paper' becomes 'tissue' (tissue is a kind of paper).
'missing leader' means to remove the first letter (leader meaning lead letter).
'tissue' with its first letter taken away is 'ISSUE'.
'of' is the link.
(Other definitions for issue that I've seen before include "Children; topic for debate" , "Topic (to be addressed)" , "important point" , "Regular publication" , "Give or send out" .)