Crossword Genius

Eerie quality of spoken words framed by good entertainers (11)

Ross

I believe the answer is:

ghostliness

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'eerie quality' is the definition.
(an eerie or ghostly atmosphere)

'spoken words framed by good entertainers' is the wordplay.
'spoken words' becomes 'lines' (I can't justify this - if you can you should believe this answer much more).
'framed by' indicates putting letters inside.
'good' becomes 'g' (abbreviation).
'entertainers' becomes 'hosts' (host is a kind of entertainer).
'g'+'hosts'='ghosts'
'lines' inserted into 'ghosts' is 'GHOSTLINESS'.

'of' acts as a link.

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