Elegantly simple opener from Hitchin Town (5)
I believe the answer is:
neath
'town' is the definition.
(town in Wales)
'elegantly simple opener from hitchin' is the wordplay.
'elegantly simple' becomes 'neat' (neat can mean simple).
'opener from' suggests taking the first letters (I've seen 'openers from' mean this (letters which open the words are used)).
The first letter of 'hitchin' is 'h'.
'neat'+'h'='NEATH'
(Other definitions for neath that I've seen before include "Welsh industrial town" , "River" , "town in South Wales" , "Lower than - a town in West Glamorgan" , "Under (poetic)" .)