Embark on a voyage (3,4)
I believe the answer is:
set sail
'embark on a voyage' is the definition.
(I've seen this in another clue)
This is all the clue.
(Other definitions for set sail that I've seen before include "Leave for (sea) voyage" , "Begin a voyage" , "Leave port (by ship)" , "have started journey" , "left land behind" .)