Emetic plant product secreted by overripe cactus (6)
I believe the answer is:
ipecac
'emetic plant product' is the definition.
(drug from ipecacuanha plant)
'secreted by overripe cactus' is the wordplay.
'secreted by' indicates a hidden word.
'IPECAC' is hidden in the letters of 'overripe cactus'.
(Other definitions for ipecac that I've seen before include "Purgative" , "That could make you sick!" , "Drug" , "that could make you puke" .)