Emotional and regularly surly after very bad flu (7)
I believe the answer is:
soulful
'emotional' is the definition.
(similar in meaning)
'regularly surly after very bad flu' is the wordplay.
'regularly' indicates alternate letters (regularly take one letter, leave next etc.).
'after' means one lot of letters go next to another.
'very' becomes 'so' (both can mean 'extremely').
'bad' indicates anagramming the letters.
The alternate letters of 'surly' are 'ul'.
'flu' with letters rearranged gives 'ful'.
'ul' after 'so' is 'soul'.
'soul'+'ful'='SOULFUL'
'and' acts as a link.
(Other definitions for soulful that I've seen before include "Expressing deep emotion" , "Heartfelt" , "Expressing (supposedly) deep feeling" , "Deeply expressive" , "Emotional" .)