Emotional disturbance produced by second white wine (5)
I believe the answer is:
shock
'emotional disturbance' is the definition.
(a shock is emotionally disturbing)
'by second white wine' is the wordplay.
'by' means one lot of letters go next to another.
'second' becomes 's' (common abbreviation).
'white wine' becomes 'hock' (hock is a kind of white wine).
's'+'hock' is 'SHOCK'.
'produced' acts as a link.
(Other definitions for shock that I've seen before include "Trauma" , "Perturb" , "Stun" , "Outrageous" , "old dog is > sixty!" .)