Emphasised more than 500 suffering anxiety (10)
I believe the answer is:
distressed
'suffering anxiety' is the definition.
'distressed' can be an answer for 'suffering' (thesaurus). I am not sure about the 'anxiety' bit.
'emphasised more than 500' is the wordplay.
'emphasised' becomes 'stressed' ('stress' can be a synonym of 'emphasize').
'more than' is a charade indicator (letters next to each other).
'500' becomes 'di' (I can't justify this - if you can you should believe this answer much more).
'stressed' after 'di' is 'DISTRESSED'.
Can you help me to learn more?
(Other definitions for distressed that I've seen before include "like Samson when deprived of his strength?" , "Upset; deliberately aged" , "in anguish?" , "Anxious" , "In deep pain or sorrow" .)