Empty cell affair causing uproar (7)
I believe the answer is:
clamour
'uproar' is the definition.
(I've seen this before)
'empty cell affair' is the wordplay.
'empty' says to hollow out the word (remove centre letters).
'affair' becomes 'amour' (amour can mean a love affair).
'cell' with its centre removed is 'cl'.
'cl'+'amour'='CLAMOUR'
'causing' is the link.
(Other definitions for clamour that I've seen before include "Hue and cry" , "racket" , "row" , "Loud and persistent outcry" , "Loud noise of shouting" .)