End of a creature outside North America (9)
I believe the answer is:
terminate
'end' is the definition.
(I know that end can be written as terminate)
'a creature outside north america' is the wordplay.
'a creature' becomes 'termite' (termite is a kind of animal).
'outside' indicates putting letters inside.
'north america' becomes 'na'.
'termite' going around 'na' is 'TERMINATE'.
'of' is the link.
(Other definitions for terminate that I've seen before include "Cut short" , "Put an end to, finish" , "Bring to an end" , "Close" , "Kill off" .)