Ending when Sue can change shades (7)
I believe the answer is:
nuances
'shades' is the definition.
('nuance' can be a synonym of 'shade')
'ending when sue can change' is the wordplay.
'ending' says to take the final letters.
'change' indicates an anagram.
The last letter of 'when' is 'n'.
'sue'+'can'='suecan'
'suecan' is an anagram of 'uances'.
'n'+'uances'='NUANCES'
(Other definitions for nuances that I've seen before include "subtle shades" , "suggestions" , "Subtleties" , "Subtle distinctions or variations" , "Fine shades (of meaning)" .)