Endless worry with one boy who played in group? (8)
I believe the answer is:
harrison
'played in group?' is the definition.
The definition suggests a singular noun which matches the answer.
'endless worry with one boy' is the wordplay.
'endless worry' becomes 'harri' (I can't justify this - if you can you should give a lot more credence to this answer).
'with' says to put letters next to each other.
'one boy' becomes 'son' (synonyms).
'harri'+'son'='HARRISON'
'who' is the link.
Can you help me to learn more?
(Other definitions for harrison that I've seen before include "Guitarist, George - actor, Rex" , "Rex ---; --- Ford" , "George maybe" , "'... Ford, film star (8)'" , "-- Birtwistle, composer" .)