English setter with guy turning around in ship (6)
I believe the answer is:
bireme
'ship' is the definition.
(I've seen this before)
'english setter with guy turning around' is the wordplay.
'english' becomes 'E' (abbreviation).
'setter' becomes 'me' (the setter of the clue).
'with' means one lot of letters go next to another.
'guy' becomes 'rib' (both can mean to tease).
'turning around' is a reversal indicator.
'e'+'me'+'rib'='emerib'
'emerib' back-to-front is 'BIREME'.
'in' acts as a link.
(Other definitions for bireme that I've seen before include "Ancient oared warship" , "Type of ancient galley" , "rowing boat" , "with two tiers" , "Ancient galley with two banks of oars on each side" .)