English team upset the Spanish one away from home (5)
I believe the answer is:
exile
'one away from home' is the definition.
(I've seen this before)
'english team upset the spanish' is the wordplay.
'english' becomes 'E' (abbreviation).
'team' becomes 'XI' (a football team, from Roman numerals for 11).
'upset' shows that the letters should be reversed in order.
'the spanish' becomes 'el' ('the' in Spanish).
'el' back-to-front is 'le'.
'e'+'xi'+'le'='EXILE'
(Other definitions for exile that I've seen before include "Jews' experience in Babylon" , "Ostracism" , "Deport" , "Person forced from country" , "One barred from their native land" .)