Enid's wrong about compassion and dismay (10)
I believe the answer is:
dishearten
'dismay' is the definition.
(I've seen this before)
'enid's wrong about compassion' is the wordplay.
'wrong' is an anagram indicator.
'about' is an insertion indicator.
'compassion' becomes 'heart' (I've seen this in another clue).
'enids' is an anagram of 'disen'.
'disen' going around 'heart' is 'DISHEARTEN'.
'and' is the link.
(Other definitions for dishearten that I've seen before include "cast down" , "dismay?" , "Put a damper on" , "Bring down" , "Cause (someone) to lose confidence" .)