Enraged drunk — one may explode (7)
I believe the answer is:
grenade
'one may explode' is the definition.
(a grenade is a type of explosive)
'enraged drunk' is the wordplay.
'drunk' indicates anagramming the letters.
'enraged' is an anagram of 'GRENADE'.
(Other definitions for grenade that I've seen before include "Hand-thrown bomb" , "One might go off" , "Small hand missile" , "Handy bomb" , "Missile thrown" .)