Entertained two Americans with edition (6)
I believe the answer is:
amused
'entertained' is the definition.
(amusing is a kind of entertaining)
'two americans with edition' is the wordplay.
'two americans' means two replacements for 'american'.
'american' becomes 'Am' (abbreviation in some contexts).
'american' becomes 'US' (United States).
'with' is a charade indicator (letters next to each other).
'edition' becomes 'ed' (abbreviation).
'am'+'us'+'ed'='AMUSED'
(Other definitions for amused that I've seen before include "Pleasantly occupied" , "was entertaining" , "Medusa (anag)" , "Tickled pink" , "Provoked mirth in" .)