Epitomise Dombey when drunk (6)
I believe the answer is:
embody
'epitomise' is the definition.
(I've seen this before)
'dombey when drunk' is the wordplay.
'when drunk' indicates anagramming the letters (a drunken or disorderly form of the letters).
'dombey' anagrammed gives 'EMBODY'.
(Other definitions for embody that I've seen before include "Represent in tangible form" , "Give a visible form to" , "Incorporate, represent" , "Epitomise" , "concretise" .)