Error from Messi's header and team's back in the lead (3-2)
I believe the answer is:
mix-up
'error' is the definition.
(mix-up is a kind of error)
'messi's header and team's back in the lead' is the wordplay.
'header' suggests taking the first letters (in a down clue, the letter at the top of the word).
'and' means one lot of letters go next to another.
'team' becomes 'xi' (eleven, a football team).
'back' is a reversal indicator.
'in the lead' becomes 'up' ('up' can be similar in meaning to 'in the lead').
The first letter of 'messi' is 'm'.
'xi' back-to-front is 'ix'.
'm'+'ix'+'up'='MIX-UP'
'from' is the link.
(Other definitions for mix-up that I've seen before include "Confused jumble" , "State of confusion or misunderstanding" , "Mistake caused by misunderstanding" , "Confused situation" .)