Escape and feel different (4)
I believe the answer is:
flee
'escape' is the definition.
(thesaurus)
'feel different' is the wordplay.
'different' indicates anagramming the letters.
'feel' is an anagram of 'FLEE'.
'and' acts as a link.
(Other definitions for flee that I've seen before include "Run quickly away" , "rush" , "Take to one's heels" , "Abscond" , "Maybe escape" .)