Estate in trouble with liqueur (8)
I believe the answer is:
anisette
'liqueur' is the definition.
(I know that anisette is a type of liqueur)
'estate in trouble' is the wordplay.
'trouble' is an anagram indicator.
'estate'+'in'='estatein'
'estatein' anagrammed gives 'ANISETTE'.
'with' acts as a link.
(Other definitions for anisette that I've seen before include "Aromatic cordial drink" , "Liqueur; tetanise (anag.)" , "Strong-flavoured liqueur" , "[APERITIF]" , "Liqueur with flavour of liquorice" .)