Crossword Genius

Estrange (8)

Ross

I believe the answer is:

alienate

'estrange' is the definition.
(synonyms)

This is the entire clue.

(Other definitions for alienate that I've seen before include "Make hostile, cause to become unfriendly" , "Eat alien in order to make hostile" , "transfer" , "Distance" , "Estrange, disaffect" .)

I've seen this clue in The Sun, the Sydney Morning Herald, the Universal, the Penny Press, the Evening Standard, The Independent and the King Feature Syndicate.
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