European associated with staggering space flight (6)
I believe the answer is:
escape
'flight' is the definition.
(synonyms)
'european associated with staggering space' is the wordplay.
'european' becomes 'E' (abbreviation e.g. EU).
'associated with' is a charade indicator (letters next to each other).
'staggering' indicates anagramming the letters (letters stagger around).
'space' anagrammed gives 'scape'.
'e'+'scape'='ESCAPE'
(Other definitions for escape that I've seen before include "Manage to avoid" , "Getaway" , "Duck" , "Elude; leakage" , "Abscond, flee" .)