European city church centre (7)
I believe the answer is:
essence
'centre' is the definition.
'european city church' is the wordplay.
'european city' becomes 'essen' (I've seen this before).
'church' becomes 'ce' (abbreviation for Church of England).
'essen'+'ce'='ESSENCE'
(Other definitions for essence that I've seen before include "Vital element" , "Perfume or concentrated extract" , "Perfume; core" , "Flavour, spirit" , "Distillate; gist" .)