Everyman will start to specify afflictions (4)
I believe the answer is:
ills
'afflictions' is the definition.
(I've seen this in another clue)
'everyman will start to specify' is the wordplay.
'everyman will' becomes 'I'll' (I will when Everyman is the setter).
'start to' indicates taking the first letters.
The first letter of 'specify' is 's'.
'ill'+'s'='ILLS'
(Other definitions for ills that I've seen before include "infections" , "Ailments, misfortunes" , "Sicknesses or harms" , "God-like" , "complaints" .)