Evil local men meet Eve in confusion (11)
I believe the answer is:
malevolence
'evil' is the definition.
(I know that evil can be written as malevolence)
'local men meet eve in confusion' is the wordplay.
'meet' is a charade indicator (letters next to each other).
'in confusion' is an anagram indicator.
'local' put after 'men' is 'menlocal'.
'menlocal'+'eve'='menlocaleve'
'menlocaleve' is an anagram of 'MALEVOLENCE'.
(Other definitions for malevolence that I've seen before include "Wickedness" , "Malice" , "unpleasant emotion" .)