Ex-vice president good to go once more (4)
I believe the answer is:
anew
'once more' is the definition.
(I've seen this in another clue)
'ex-vice president good to go' is the wordplay.
'ex-vice president' becomes 'Agnew' (Spiro Agnew, US vice president 1969-1973).
'good' becomes 'g' (abbreviation).
'to go' is a deletion indicator.
'agnew' with 'g' taken away is 'ANEW'.
(Other definitions for anew that I've seen before include "Once more (poetic)" , "Wane in a different way, again" , "From the beginning again" , "Again but differently" , "Afresh" .)