Exaggeratedly masculine (5)
(Other definitions for macao that I've seen before include "Portuguese province" , "Former Portuguese colony in China" , "Eastern city" .)
'exaggeratedly masculine' is the definition.
(I've seen this before)
This is the entire clue.
(Other definitions for macho that I've seen before include "Affectedly virile" , "Ultra-masculine" , "Ostentatiously virile" , "Typically tough (guy)" , "Laddish" .)