Examination of drunk about rupture inside (6)
I believe the answer is:
tripos
'examination' is the definition.
(tripos is a kind of examination)
'drunk about rupture inside' is the wordplay.
'drunk' becomes 'sot' ('sot' can be a synonym of 'drunk').
'about' shows that the letters should be reversed in order.
'rupture' becomes 'rip' (ripping is a kind of rupturing).
'inside' is an insertion indicator.
'sot' in reverse letter order is 'tos'.
'tos' going around 'rip' is 'TRIPOS'.
'of' is the link.
(Other definitions for tripos that I've seen before include "important examination" , "university exam" , "Cambridge honours examination" , "Final honours exam for Cambridge BA" .)