Exercise before second drink (5-2)
I believe the answer is:
press-up
'exercise' is the definition.
(press-up is a kind of exercise)
'before second drink' is the subsidiary indication.
'before' becomes 'pre'.
'second' becomes 's' (common abbreviation).
'drink' becomes 'sup' (I've seen this before**).
'pre'+'s'+'sup'='pressup'
(Other definitions for press-up that I've seen before include "Form of arm exercise" , "Keep-fit exercise" , "Face-to-the-floor exercise" , "Gymnastic floor exercise" , "PE exercise" .)